The Roles of C-X-C Motif Chemokine Ligand 10 (CXCL10) in Dengue

Early diagnosis of dengue is crucial to prevent the progression severe (SD) leading mortality rate reduction. This study aimed determine role CXCL10 in and its potential utilization as one biomarkers for early dengue. A case-control was conducted involving healthy subjects control (n = 10) 193 cases. The cases were categorized into without warning signs (DwoWS: n 70; 34.5 %), with (DWWS: 108; 23.2 (SD: 15; 7.4 %). socio-demographic characteristics, clinical presentations, laboratory parameters (platelet hematocrit) documented. Serum quantification performed using an enzyme-linked immunosorbent assay (ELISA). descriptive analysis Pearson’s correlation test used analyze demographic data between CXCL10, hematocrit, platelet respectively. difference age (p 0.02) ethnicity significant control. Males more frequently had SD contrast females (4:1). frequent abdominal pain (42.0 vomiting (38.3 bleeding tendency (15.0 fluid accumulation (7.2 increase hematocrit 0.039) reduction 0.0005) SD. mean (134.85 ± 48.52 rg/mL) significantly lower than (545.22 76.33 rg/mL, p 0.0005). evident be a biomarker